Reversing Type 1 Diabetes

The Faustman Lab at Massachusetts General Hospital has been working on a vaccine for Type 1 Diabetes using a generic drug Bacillus Calmette-Guerin (BCG).  The experiments have passed every research milestone ahead of schedule and and the Phase I safety trial in humans is almost complete.  In Phase II they will study the dosage and frequency of the administration to reverse Type 1 Diabetes.  The kicker in all of this is that BCG is a generic drug that has been in use for over 80 years as a vaccine.  BCG has the ability to attack and destroy auto-immune disorder causing T-cells while causing the release of new healthy T-cells at the same time.  BCG also does not attack the healthy T-cells so the autoimmune system is left in-tact.  With the immune system working properly it allows the pancreas to regenerate the islet cells and start producing insulin again. I hope the second phase of the testing works as well as the first, as much as I like the idea of being a cyborg, I like the idea of not having to worry about pricking my fingers, replacing pods, insulin and batteries and being healthy a whole lot more.

A much more in-depth article about the research can be read here and more information about the Faustman Lab is here.

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